[HTML][HTML] Validation of a digital pathology system including remote review during the COVID-19 pandemic

MG Hanna, VE Reuter, O Ardon, D Kim, SJ Sirintrapun… - Modern Pathology, 2020 - Elsevier
Remote digital pathology allows healthcare systems to maintain pathology operations
during public health emergencies. Existing Clinical Laboratory Improvement Amendments …

[HTML][HTML] Whole slide imaging equivalency and efficiency study: experience at a large academic center

MG Hanna, VE Reuter, MR Hameed, LK Tan… - Modern Pathology, 2019 - Elsevier
Whole slide imaging is Food and Drug Administration-approved for primary diagnosis in the
United States of America; however, relatively few pathology departments in the country have …

The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data

A McKenna, M Hanna, E Banks, A Sivachenko… - Genome …, 2010 - genome.cshlp.org
Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are
already revolutionizing our understanding of genetic variation among individuals. However, …

[HTML][HTML] Integrating digital pathology into clinical practice

MG Hanna, O Ardon, VE Reuter, SJ Sirintrapun… - Modern Pathology, 2022 - Elsevier
The field of anatomic pathology has been evolving in the last few decades and the advancements
have been largely fostered by innovative technology. Immunohistochemistry enabled …

Clinical-grade computational pathology using weakly supervised deep learning on whole slide images

G Campanella, MG Hanna, L Geneslaw, A Miraflor… - Nature medicine, 2019 - nature.com
The development of decision support systems for pathology and their deployment in clinical
practice have been hindered by the need for large manually annotated datasets. To …

A framework for variation discovery and genotyping using next-generation DNA sequencing data

…, AA Philippakis, G Del Angel, MA Rivas, M Hanna… - Nature …, 2011 - nature.com
Recent advances in sequencing technology make it possible to comprehensively catalog
genetic variation in population samples, creating a foundation for understanding human …

Metastasis and immune evasion from extracellular cGAMP hydrolysis

…, MP Humphries, M Salto-Tellez, JA James, MG Hanna… - Cancer discovery, 2021 - AACR
Chromosomal instability promotes metastasis by generating chronic tumor inflammation.
ENPP1 facilitates metastasis and enables tumor cells to tolerate inflammation by hydrolyzing …

Estimation of aerobic fitness from 20-m multistage shuttle run test performance

MT Mahar, AM Guerieri, MS Hanna… - American journal of …, 2011 - Elsevier
BACKGROUND: Aerobic fitness (VO 2 max) is a key component of youth fitness testing.
Criterion-referenced (CR) assessments are used in FITNESSGRAM ® to assess health risk. …

Augmented reality technology using Microsoft HoloLens in anatomic pathology

MG Hanna, I Ahmed, J Nine… - … of pathology & …, 2018 - meridian.allenpress.com
Context Augmented reality (AR) devices such as the Microsoft HoloLens have not been well
used in the medical field. Objective To test the HoloLens for clinical and nonclinical …

[HTML][HTML] Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group

…, S Goel, HC Lien, S Loibl, Z Kos, S Loi, MG Hanna… - NPJ breast …, 2020 - nature.com
Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral
part of the prognostic workflow in triple-negative (TNBC) and HER2-positive breast cancer, …